منابع مشابه
ADAMTS proteinases: a multi-domain, multi-functional family with roles in extracellular matrix turnover and arthritis
Members of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) family are known to influence development, angiogenesis, coagulation and progression of arthritis. As proteinases their substrates include the von Willebrand factor precursor and extracellular matrix components such as procollagen, hyalectans (hyaluronan-binding proteoglycans including aggrecan), decorin, fib...
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1. Woywodt A, Haubitz M, Haller H, Matteson EL: Wegener’s granulomatosis. Lancet 367: 1362–1366, 2006 2. Klinger H: Grenzformen der Periarteriitis Nodosa. Frankf Z Pathol 42: 455–480, 1931 3. Wegener F: Ueber generalisierte septische Gefäßerkrankungen. Verh Deut Pathol Ges 29: 202–210, 1936 4. Wegener F: Ueber eine eigenartige rhinogene Granulomatose mit besonderer Beteiligung des Arteriensyste...
متن کاملDental Enamel Development: Proteinases and Their Enamel Matrix Substrates
This review focuses on recent discoveries and delves in detail about what is known about each of the proteins (amelogenin, ameloblastin, and enamelin) and proteinases (matrix metalloproteinase-20 and kallikrein-related peptidase-4) that are secreted into the enamel matrix. After an overview of enamel development, this review focuses on these enamel proteins by describing their nomenclature, tis...
متن کاملBrain matrix: structure, turnover and necessity.
Aided by mice with multiple deleted brain matrix protein genes, the biochemical analysis of mouse brain matrix molecules indicates a constitutive production of more proteoglycans than can be integrated in multimolecular matrix structures. Possible functions of non-matrix integrated proteoglycans, and aspects of incomplete compensatory mechanisms in knockout mice are discussed.
متن کاملMultiple Secretion of Matrix Serine Proteinases by Human Gastric Carcinoma
Proli'¡misespecies secreted by 10 human gastric carcinoma cell lines were analyzed by gelatin zymography and immunoblotting. These cell lines were classified into the following three groups with respect to proteinase secretion: cell lines secreting mainly gelatinases A and/or B; those secreting multiple types of serine proteinases; and those scarcely secreting these enzymes. Two cell lines of ...
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ژورنال
عنوان ژورنال: Kidney International
سال: 1992
ISSN: 0085-2538
DOI: 10.1038/ki.1992.103